SCHEMBL7537635

SCHEMBL7537635

Cc1ccc(O)cc1N1CCN([C@H]2Cc3c(I)cccc3C[C@@H]2O)CC1

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 11/20 0.47
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7537639 1.00 SLC18A3 (0.47) SLC18A3ALDH1A1LMNA
SCHEMBL7536770 0.90 SLC18A3 (0.58) SLC18A3ALDH1A1LMNA
SCHEMBL7536758 0.90 SLC18A3 (0.58) SLC18A3ALDH1A1LMNA
SCHEMBL7536763 0.90 SLC18A3 (0.58) SLC18A3ALDH1A1LMNA
SCHEMBL7543273 0.87 SLC18A3 (0.54) SLC18A3
SCHEMBL7543279 0.87 SLC18A3 (0.54) SLC18A3
SCHEMBL7537073 0.86 SLC18A3 (0.57) SLC18A3ALDH1A1
SCHEMBL7537080 0.86 SLC18A3 (0.57) SLC18A3ALDH1A1
SCHEMBL7537075 0.86 SLC18A3 (0.57) SLC18A3ALDH1A1
SCHEMBL7537808 0.86 SLC18A3 (0.45) SLC18A3ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1205473-A1 VESAMICOL PIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) 2002-05-15 EP disclosed