Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 6/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537803 | 1.00 | SLC18A3 (0.45) | SLC18A3HTR1ANPC1RECQLALDH1A1 | |
| SCHEMBL7539360 | 0.88 | SLC18A3 (0.51) | SLC18A3HTR1A | |
| SCHEMBL7539362 | 0.88 | SLC18A3 (0.51) | SLC18A3HTR1A | |
| SCHEMBL7536758 | 0.87 | SLC18A3 (0.58) | SLC18A3ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL7536763 | 0.87 | SLC18A3 (0.58) | SLC18A3ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL7536770 | 0.87 | SLC18A3 (0.58) | SLC18A3ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL7537639 | 0.86 | SLC18A3 (0.47) | SLC18A3ALDH1A1LMNA | |
| SCHEMBL7537635 | 0.86 | SLC18A3 (0.47) | SLC18A3ALDH1A1LMNA | |
| SCHEMBL7537075 | 0.83 | SLC18A3 (0.57) | SLC18A3ALDH1A1TSHR | |
| SCHEMBL7537080 | 0.83 | SLC18A3 (0.57) | SLC18A3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1205473-A1 | VESAMICOL PIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |