Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541915 | 1.00 | CETP (0.52) | CETPALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL28667905 | 0.98 | ALDH1A1 (0.52) | CETPALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL28147418 | 0.94 | ALDH1A1 (0.54) | CETPALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL28663034 | 0.93 | TSHR (0.58) | CETPALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL28647837 | 0.93 | ALDH1A1 (0.55) | CETPALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL17377648 | 0.92 | ALDH1A1 (0.48) | CETPALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL28557157 | 0.90 | ALDH1A1 (0.49) | CETPALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL28657532 | 0.90 | PTPN1 (0.49) | CETPALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL28665500 | 0.90 | ALDH1A1 (0.55) | CETPALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL28123741 | 0.90 | ALDH1A1 (0.50) | CETPALDH1A1MAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200454-A1 | BISPLATINUM COMPLEXES ACTIVE THROUGH THE ORAL ROUTE | Novuspharma S.p.A. (IT) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009149-A1 | BISPLATINUM COMPLEXES ACTIVE THROUGH THE ORAL ROUTE | NOVUSPHARMA S.P.A. (IT) | 2001-02-08 | — | — | WO | disclosed |