SCHEMBL7538255

SCHEMBL7538255

Nc1ccc(C(=O)Nc2cc(NC(=O)c3ccc(N)cc3)cc(C(=O)O)c2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.70
KMT2A Q03164 5/20 0.70
POLB P06746 3/20 0.70
PKM P14618 2/20 0.67
LMNA P02545 1/20 0.67
APEX1 P27695 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
L3MBTL1 Q9Y468 2/20 0.61
PTGS1 P23219 2/20 0.54
P2RY14 Q15391 2/20 0.54
FABP1 P07148 1/20 0.54
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
SNCA P37840 1/20 0.51
MAPT P10636 1/20 0.51
HPSE Q9Y251 1/20 0.51
PRMT1 Q99873 1/20 0.50
MITF O75030 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL529184 0.96 MEN1 (0.67) MEN1KMT2APOLBPKMLMNA
SCHEMBL6265712 0.87 L3MBTL1 (0.78) MEN1KMT2APOLBPKML3MBTL1
SCHEMBL7877076 0.85 POLB (0.85) MEN1KMT2APOLBPKMLMNA
SCHEMBL17795755 0.85 POLB (0.85) MEN1KMT2APOLBPKMLMNA
SCHEMBL3277058 0.85 POLB (0.85) MEN1KMT2APOLBPKMLMNA
SCHEMBL28154869 0.85 L3MBTL1 (0.75) MEN1KMT2APOLBPKML3MBTL1
SCHEMBL6865518 0.85 HPSE (0.72) MEN1KMT2APOLBPKMLMNA
SCHEMBL13900833 0.84 KMT2A (0.65) MEN1KMT2APOLBPKMLMNA
SCHEMBL10042212 0.84 L3MBTL1 (0.58) MEN1KMT2APOLBPKMLMNA
SCHEMBL10034909 0.84 MEN1 (0.69) MEN1KMT2APOLBPKMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523889-B2 Liquid crystal display unit and method of manufacturing the same SONY CORPORATION (JP) 2016-12-20 US disclosed
US-9507210-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2016-11-29 US disclosed
US-9470929-B2 Liquid crystal display unit and method of manufacturing the same SONY CORPORATION (JP) 2016-10-18 US disclosed
US-9366910-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2016-06-14 US disclosed
US-20160011463-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2016-01-14 US disclosed
US-9146425-B2 Liquid crystal display and method of manufacturing the same SONY CORPORATION (JP) 2015-09-29 US disclosed
US-20150146148-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2015-05-28 US disclosed
US-20140170926-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2014-06-19 US disclosed
US-20130155360-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2013-06-20 US disclosed
US-20130010244-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION 2013-01-10 US disclosed
US-20120212697-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2012-08-23 US disclosed
US-20120026440-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME SONY CORPORATION (JP) 2012-02-02 US disclosed
US-20110273652-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-11-10 US disclosed
EP-2383605-A2 Liquid crystal display device with adjusted pretilt angles for the liquid crystal molecules and method for manufacturing the display device Sony Corporation (JP) 2011-11-02 EP disclosed
EP-1209185-A1 DIAMINOBENZENE DERIVATIVE, POLYIMIDE OBTAINED THEREFROM, AND LIQUID-CRYSTAL ALIGNMENT FILM Nissan Chemical Industries, Ltd. (JP) 2002-05-29 EP disclosed
US-4529793-A Selective permeable membranes comprising a polyquinazolone-based polymer NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1985-07-16 US disclosed
US-4354017-A Process for the production of polyquinazolone-based polymers NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160011463-A1 LIQUID CRYSTAL DISPLAY UNIT AND METHOD OF MANUFACTURING THE SAME PYM1, PDCD2L, SDAD1 MEN1 2607/4885KMT2A 3545/4885POLB 3392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.