Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537746 | 0.93 | HDAC4 (0.54) | HDAC4TP53RORCTSHRBRPF1 | |
| SCHEMBL5163474 | 0.87 | HDAC4 (0.64) | HDAC4TP53RORCTSHRBRPF1 | |
| SCHEMBL7535425 | 0.86 | HDAC4 (0.62) | HDAC4TSHRMAPTMEN1KMT2A | |
| SCHEMBL8151209 | 0.86 | HDAC4 (0.39) | HDAC4TP53TSHRHIF1AMEN1 | |
| SCHEMBL7620493 | 0.86 | HDAC4 (0.39) | HDAC4TP53TSHRHIF1ATHRB | |
| SCHEMBL8151208 | 0.85 | HDAC4 (0.38) | HDAC4TP53TSHRHIF1AMAPT | |
| SCHEMBL5165770 | 0.82 | HDAC4 (0.59) | HDAC4TP53TSHRBRPF1HIF1A | |
| SCHEMBL5163897 | 0.82 | HDAC4 (0.64) | HDAC4TP53RORCTSHRBRPF1 | |
| SCHEMBL7533271 | 0.80 | HDAC4 (0.40) | HDAC4TP53RORCTSHRHIF1A | |
| SCHEMBL6999887 | 0.79 | HDAC4 (0.78) | HDAC4RORCTSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020173520-A1 | Quinoline derivatives | ACTIVE BIOTECH AB (SE) | 2002-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173520-A1 | Quinoline derivatives | CYP4F3, IRF3, CXCR3 | HDAC4 2957/4885TP53 2677/4885RORC 603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.