Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538494 | 1.00 | MAPT (0.37) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7538334 | 0.95 | GAA (0.38) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7538333 | 0.95 | GAA (0.38) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7541822 | 0.93 | ACE (0.37) | MAPTRENMMP2MMP9MMP7 | |
| SCHEMBL7541816 | 0.93 | ACE (0.37) | MAPTRENMMP2MMP9MMP7 | |
| SCHEMBL7538603 | 0.92 | MMP2 (0.39) | MAPTMEN1KMT2AALDH1A1REN | |
| SCHEMBL7538599 | 0.92 | MMP2 (0.39) | MAPTMEN1KMT2AALDH1A1REN | |
| SCHEMBL7538788 | 0.88 | PSMB11 (0.39) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7538783 | 0.88 | PSMB11 (0.39) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7544077 | 0.88 | MAPK1 (0.42) | MAPTRENMMP2MMP9MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |