Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 19/20 | 0.59 |
| ▸ | ITGA4 | P13612 | 17/20 | 0.59 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.59 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.59 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918854 | 0.95 | ITGB1 (0.55) | ITGB1ITGA4ITGB7ITGA2ITGA5 | |
| SCHEMBL5782600 | 0.94 | ITGB1 (0.54) | ITGB1ITGA4ITGB7ITGA2ITGA5 | |
| SCHEMBL5801107 | 0.90 | ITGA4 (0.56) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL27702074 | 0.89 | ITGB1 (0.78) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL6638839 | 0.89 | ITGB1 (0.78) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL27519575 | 0.87 | ITGB1 (0.56) | ITGB1ITGA4ITGB7ITGA2ITGA5 | |
| SCHEMBL920419 | 0.87 | ITGB1 (0.56) | ITGB1ITGA4ITGB7ITGA2ITGA5 | |
| SCHEMBL13726463 | 0.87 | ATM (0.59) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL5786018 | 0.86 | ITGA4 (0.54) | ITGB1ITGA4ITGB7 | |
| SCHEMBL919732 | 0.86 | ITGB1 (0.49) | ITGB1ITGA4ITGB7ITGA2ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |