Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | HRH1 | P35367 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CPN1 | P15169 | 2/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14574040 | 1.00 | CHRM1 (0.60) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL5515416 | 0.90 | SMN1; SMN2 (0.54) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL18050479 | 0.90 | SMN1; SMN2 (0.54) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL15204045 | 0.88 | CA2 (0.59) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL7369426 | 0.87 | CPN1 (0.65) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL15204003 | 0.85 | GRIK1 (0.53) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL5379218 | 0.85 | GRIK1 (0.53) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL13747339 | 0.83 | CPN1 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL6393775 | 0.82 | CA1 (0.44) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL7372259 | 0.81 | CPN1 (0.55) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020156320-A1 | Enantioselective synthesis of valproic acid analogues | NAU HEINZ (DE) | 2002-10-24 | — | — | US | claimed |
| US-20020156320-A1 | Enantioselective synthesis of valproic acid analogues | NAU HEINZ (DE) | 2002-10-24 | — | — | US | disclosed |
| WO-2001051449-A1 | METHOD FOR PRODUCING ENANTIOMER-PURE ANALOGS OF VALPROIC ACID | NAU HEINZ (DE) | 2001-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156320-A1 | Enantioselective synthesis of valproic acid analogues | COASY, ACADM, CYP2A6 | CHRM1 3665/4885AKR1A1 297/4885CHRM3 3189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.