Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 6/20 | 0.80 |
| ▸ | CXCR1 | P25024 | 5/20 | 0.80 |
| ▸ | MEN1 | O00255 | 5/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.80 |
| ▸ | DDX3X | O00571 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595006 | 0.93 | CXCR1 (0.74) | CXCR2CXCR1MEN1KMT2ATDP1 | |
| SCHEMBL29733649 | 0.90 | CXCR2 (1.00) | CXCR2CXCR1MEN1KMT2ATDP1 | |
| SCHEMBL1110610 | 0.90 | CXCR2 (1.00) | CXCR2CXCR1MEN1KMT2ATDP1 | |
| SCHEMBL6921874 | 0.90 | CXCR2 (1.00) | CXCR2CXCR1MEN1KMT2ATDP1 | |
| SCHEMBL29493172 | 0.90 | CXCR2 (1.00) | CXCR2CXCR1MEN1KMT2ATDP1 | |
| SCHEMBL5594608 | 0.82 | CXCR2 (0.76) | CXCR2CXCR1MEN1KMT2ATDP1 | |
| SCHEMBL31222305 | 0.82 | CXCR2 (1.00) | CXCR2CXCR1MEN1KMT2ATDP1 | |
| SCHEMBL5595180 | 0.82 | CXCR2 (1.00) | CXCR2CXCR1MEN1KMT2ATDP1 | |
| SCHEMBL11846997 | 0.82 | RAB9A (0.73) | CXCR2CXCR1MEN1KMT2ADDX3X | |
| SCHEMBL7493083 | 0.81 | CXCR2 (0.74) | CXCR2CXCR1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896531-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-0896531-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997029743-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-21 | — | — | WO | disclosed |