SCHEMBL7539620

SCHEMBL7539620

CO/N=C(/C(N)=O)c1ccccc1COc1ccc(Cl)cc1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.62
MAOB P27338 2/20 0.46
MAOA P21397 1/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
NR4A2 P43354 1/20 0.44
OPRL1 P41146 4/20 0.44
PARP10 Q53GL7 2/20 0.43
PARP15 Q460N3 1/20 0.43
PARP14 Q460N5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8881114 0.87 HIF1A (0.64) HIF1AMAOBMAOANPC1RAB9A
SCHEMBL8990678 0.87 HIF1A (0.64) HIF1AMAOBMAOANPC1RAB9A
SCHEMBL8369619 0.86 HIF1A (0.62) HIF1AMAOBMAOANPC1RAB9A
SCHEMBL8369617 0.86 HIF1A (0.62) HIF1AMAOBMAOANPC1RAB9A
SCHEMBL9215719 0.83 HIF1A (0.52) HIF1A
SCHEMBL9215724 0.83 HIF1A (0.52) HIF1A
SCHEMBL7535120 0.81 HIF1A (0.57) HIF1AMAOBMAOANPC1RAB9A
SCHEMBL8624085 0.80 HIF1A (0.62) HIF1AMAOBMAOANPC1RAB9A
SCHEMBL8624082 0.80 HIF1A (0.62) HIF1AMAOBMAOANPC1RAB9A
SCHEMBL8623305 0.79 HIF1A (0.65) HIF1AMAOBNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362212-B1 POTENT FUNGICIDAL ACTIVITY SHIONOGI & COMPANY, LTD. (JP) 2002-03-26 US disclosed
US-20020032227-A1 Oxime derivative and bactericide containing the same as active ingredient TAKASE AKIRA (JP) 2002-03-14 US disclosed
US-6268312-B1 FUNGICIDES SHIONOGI & CO., LTD. (JP) 2001-07-31 US disclosed
US-6048885-A FUNGICIDES SHIONOGI & CO., LTD. (JP) 2000-04-11 US disclosed
EP-0754684-A1 OXIME DERIVATIVE AND BACTERICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT SHIONOGI & CO., LTD. (JP) 1997-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020032227-A1 Oxime derivative and bactericide containing the same as active ingredient MSMO1, O60361, CBR1 HIF1A 3592/4885MAOB 464/4885MAOA 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.