SCHEMBL8881114

SCHEMBL8881114

CON=C(C(N)=O)c1ccccc1COc1cccc(Cl)c1

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.64
OPRL1 P41146 1/20 0.46
POLB P06746 1/20 0.46
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
RXRG P48443 1/20 0.45
MAOA P21397 3/20 0.44
MAOB P27338 3/20 0.44
NR4A2 P43354 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8990678 1.00 HIF1A (0.64) HIF1AOPRL1POLBRXRARXRB
SCHEMBL7539620 0.87 HIF1A (0.62) HIF1AOPRL1MAOAMAOBNR4A2
SCHEMBL8065565 0.87 HIF1A (0.51) HIF1AOPRL1POLBRXRARXRB
SCHEMBL8065563 0.87 HIF1A (0.51) HIF1AOPRL1POLBRXRARXRB
SCHEMBL6451814 0.87 HIF1A (0.65) HIF1AOPRL1RXRARXRBRXRG
SCHEMBL6451811 0.87 HIF1A (0.65) HIF1AOPRL1RXRARXRBRXRG
SCHEMBL8368443 0.87 HIF1A (0.65) HIF1AOPRL1RXRARXRBRXRG
SCHEMBL28770156 0.84 HIF1A (0.80) HIF1AMAOAMAOBNR4A2NPC1
SCHEMBL28770154 0.84 HIF1A (0.80) HIF1AMAOAMAOBNR4A2NPC1
SCHEMBL9215724 0.82 HIF1A (0.52) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4288045-A None JP disclosed
JP-7187918-A None JP disclosed
US-5677347-A FUNGICIDES, PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-10-14 US disclosed
US-5523454-A FUNGICIDES, PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-06-04 US disclosed
US-5516804-A FUNGICIDES FOR PLANTS BASF AKTIENGESELLSCHAFT (DE) 1996-05-14 US disclosed
JP-H07187918-A FUNGICIDE COMPOSITION SUMITOMO CHEM CO LTD 1995-07-25 JP disclosed
US-5395854-A Fungicides BASF AKTIENGESELLSCHAFT (DE) 1995-03-07 US disclosed
JP-H04288045-A ORTHO-SUBSTITUTED PHENYLACETAMIDE BASF AG 1992-10-13 JP disclosed