Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA3 | P07451 | 2/20 | 0.78 |
| ▸ | CA5A | P35218 | 2/20 | 0.78 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.78 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.78 |
| ▸ | CA12 | O43570 | 1/20 | 0.78 |
| ▸ | CA2 | P00918 | 1/20 | 0.78 |
| ▸ | CA4 | P22748 | 1/20 | 0.78 |
| ▸ | CA6 | P23280 | 1/20 | 0.78 |
| ▸ | CA7 | P43166 | 1/20 | 0.78 |
| ▸ | CA9 | Q16790 | 1/20 | 0.78 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18502181 | 0.96 | EPHX1 (0.79) | CA3CA5ACA5BCA14CA12 | |
| SCHEMBL2736707 | 0.92 | EPHX1 (0.84) | CA3CA5ACA5BCA14CA12 | |
| SCHEMBL3142216 | 0.90 | CA3 (0.95) | CA3CA5ACA5BCA14CA12 | |
| SCHEMBL7539898 | 0.89 | CA3 (0.78) | CA3CA5ACA5BCA14CA12 | |
| SCHEMBL10228415 | 0.88 | CA3 (1.00) | CA3CA5ACA5BCA14CA12 | |
| SCHEMBL1274081 | 0.88 | CA3 (1.00) | CA3CA5ACA5BCA14CA12 | |
| SCHEMBL12936102 | 0.88 | CA3 (1.00) | CA3CA5ACA5BCA14CA12 | |
| SCHEMBL467174 | 0.86 | CA3 (0.74) | CA3CA5ACA5BCA14CA12 | |
| SCHEMBL1389225 | 0.86 | EPHX1 (0.96) | CA3CA5ACA5BCA14CA12 | |
| SCHEMBL7716931 | 0.84 | EPHX1 (1.00) | CA3CA5ACA5BCA14CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200454-A1 | BISPLATINUM COMPLEXES ACTIVE THROUGH THE ORAL ROUTE | Novuspharma S.p.A. (IT) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009149-A1 | BISPLATINUM COMPLEXES ACTIVE THROUGH THE ORAL ROUTE | NOVUSPHARMA S.P.A. (IT) | 2001-02-08 | — | — | WO | disclosed |