Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9565026 | 0.99 | HTT (0.43) | HTTSMN1; SMN2HIF1ALMNATGM2 | |
| Bromide SCHEMBL10633645 | 0.99 | HTT (0.43) | HTTSMN1; SMN2HIF1ALMNATGM2 | |
| SCHEMBL27630879 | 0.86 | HTT (0.45) | HTTSMN1; SMN2HIF1ALMNATGM2 | |
| SCHEMBL9301763 | 0.81 | CTSL (0.45) | TGM2ALDH1A1 | |
| SCHEMBL17107854 | 0.81 | HTT (0.40) | HTTSMN1; SMN2LMNATGM2KEAP1 | |
| SCHEMBL3821244 | 0.81 | HTT (0.40) | HTTSMN1; SMN2LMNATGM2KEAP1 | |
| SCHEMBL3628582 | 0.81 | HTT (0.40) | HTTSMN1; SMN2LMNATGM2KEAP1 | |
| SCHEMBL10855143 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1ALMNASLC6A2SLC6A3 | |
| SCHEMBL10855149 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1ALMNASLC6A2SLC6A3 | |
| SCHEMBL27484782 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2HIF1ALMNASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204671-A1 | FLUOROGENIC COMPOUNDS AND USES THEREFOR | 3M Innovative Properties Company (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001010881-A1 | FLUOROGENIC COMPOUNDS AND USES THEREFOR | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-02-15 | — | — | WO | disclosed |
| US-4810631-A | BLOCKED CATALYST INHIBITOR | BECTON, DICKINSON AND COMPANY (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0042291-B1 | METHODS AND COMPOSITIONS FOR PREPARATION OF H-ARG-X-Z-Y-TYR-R | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-12-10 | — | — | EP | disclosed |