SCHEMBL7540125

SCHEMBL7540125

Nc1nccc2ccc(CN3CC[C@H](NS(=O)(=O)c4cc5ncccc5s4)C3=O)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 19/20 1.00
PRSS1 P07477 6/20 0.69
PROC P04070 5/20 0.69
PLAT P00750 3/20 0.69
F2 P00734 6/20 0.61
PLG P00747 4/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12589596 1.00 F10 (1.00) F10PRSS1PROCPLATF2
Trifluoroacetic Acid SCHEMBL7545759 0.94 F10 (0.88) F10PRSS1PROCPLATF2
Trifluoroacetic Acid SCHEMBL7538088 0.94 F10 (0.88) F10PRSS1PROCPLATF2
SCHEMBL7539523 0.91 F10 (0.83) F10PRSS1PROCPLATF2
SCHEMBL7536954 0.89 F10 (0.80) F10PRSS1PROCPLATF2
SCHEMBL6220735 0.88 F10 (1.00) F10PRSS1PROCPLATF2
SCHEMBL7538068 0.88 F10 (0.79) F10PRSS1PROCPLATF2
Trifluoroacetic Acid SCHEMBL7541583 0.84 F10 (0.73) F10PRSS1PROCPLATF2
SCHEMBL7540352 0.81 F10 (0.68) F10PRSS1PROCPLATF2
Trifluoroacetic Acid SCHEMBL7505792 0.80 F10 (0.67) F10PRSS1PROCPLATF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020013310-A1 Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds AVENTIS PHARMACEUTICALS PRODUCTS INC. 2002-01-31 US claimed
US-20020013310-A1 Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds AVENTIS PHARMACEUTICALS PRODUCTS INC. 2002-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020013310-A1 Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds STS, ARSA, F12 F10 20/4885PRSS1 67/4885PROC 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.