Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547973 | 0.82 | HTR2A (0.39) | KDM4EALDH1A1MAPTHTTPTGS2 | |
| SCHEMBL7540781 | 0.81 | MAPK1 (0.38) | KDM4ECYP1A2ALDH1A1TDP1HPGD | |
| SCHEMBL7543629 | 0.80 | KMT2A (0.37) | KDM4EALDH1A1TDP1HPGDGLA | |
| SCHEMBL7543632 | 0.80 | TDP1 (0.33) | KDM4ECYP1A2ALDH1A1TDP1HPGD | |
| SCHEMBL7546763 | 0.78 | GRIN2D (0.36) | KDM4EALDH1A1POLBKMT2AMEN1 | |
| Nitrous Acid SCHEMBL7549271 | 0.77 | HTR2A (0.36) | KDM4EMAPTHTTPTGS2 | |
| SCHEMBL30439274 | 0.68 | TDP1 (0.51) | KDM4EALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL2494137 | 0.68 | TDP1 (0.51) | KDM4EALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL25280185 | 0.67 | TDP1 (0.51) | KDM4EALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL14142210 | 0.67 | KDM4E (0.44) | KDM4ECYP1A2ALDH1A1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883599-B1 | AMINOTETRALIN DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF | ASTRAZENECA AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| US-5807897-A | MUSCULAR DISORDERS | ZENECA LIMITED (GB) | 1998-09-15 | — | — | US | disclosed |