Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.32 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3861595 | 0.75 | CYP11B1 (0.37) | ATMKMT2ANPC1RAB9ATP53 | |
| SCHEMBL7537847 | 0.72 | KMT2A (0.33) | KMT2AGPR139CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL8385586 | 0.70 | ATM (0.32) | ATM | |
| Tibenzate SCHEMBL2110094 | 0.65 | IDO1 (0.52) | KMT2AGPR139SMN1; SMN2CYP2C19PTPN1 | |
| SCHEMBL7538966 | 0.65 | KMT2A (0.32) | KMT2AGPR139NPC1RAB9ASMN1; SMN2 | |
| Phosphonic Acid SCHEMBL8386850 | 0.64 | ATM (0.32) | ATM | |
| SCHEMBL7543251 | 0.64 | SIRT2 (0.39) | KMT2ARAB9ACYP1A2CYP2C19HPGD | |
| SCHEMBL9543154 | 0.64 | ALDH1A1 (0.30) | ATMSMN1; SMN2ALDH1A1 | |
| SCHEMBL19743582 | 0.63 | CYP2C19 (0.49) | KMT2AGPR139SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL1562665 | 0.63 | TSHR (0.42) | KMT2ANPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468995-B1 | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0667868-B1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-05-15 | — | — | EP | disclosed |
| CN-1116425-A | New cephem compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-02-07 | — | — | CN | disclosed |
| WO-1995007283-A1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-16 | — | — | WO | disclosed |