Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9592586 | 0.86 | PKMYT1 (0.36) | GRM5ALDH1A1 | |
| SCHEMBL24069013 | 0.83 | ALDH1A1 (0.37) | KMT2AMEN1GRM5GABRPGABRD | |
| SCHEMBL29432473 | 0.83 | ALDH1A1 (0.41) | KMT2AMEN1GRM5GABRPGABRD | |
| SCHEMBL6100470 | 0.83 | ALDH1A1 (0.41) | KMT2AMEN1GRM5GABRPGABRD | |
| SCHEMBL30206297 | 0.82 | GRM5 (0.42) | KMT2AMEN1GRM5GABRPGABRD | |
| SCHEMBL1674128 | 0.82 | GRM5 (0.42) | KMT2AMEN1GRM5GABRPGABRD | |
| SCHEMBL30112052 | 0.81 | HPGD (0.39) | KMT2AMEN1GRM5GABRPGABRD | |
| SCHEMBL7422568 | 0.81 | HPGD (0.39) | KMT2AMEN1GRM5GABRPGABRD | |
| SCHEMBL27479483 | 0.81 | ALDH1A1 (0.40) | KMT2AMEN1GRM5GABRPGABRD | |
| SCHEMBL27559489 | 0.78 | ALDH1A1 (0.37) | KMT2AMEN1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369545-B | Synthesis process of 2-methyl-5-pyrazine formate | 东营曜康医药科技有限公司 | 2020-04-10 | — | — | CN | claimed |
| US-5364940-A | For treatment of sewage sludge with cultures | LONZA LTD. (CH) | 1994-11-15 | — | — | US | claimed |
| EP-0559116-A2 | Microbiological process for the hydroxylation of nitrogen containing heterocyclic carbonic acids | LONZA AG (CH) | 1993-09-08 | — | — | EP | claimed |
| CN-109369545-B | Synthesis process of 2-methyl-5-pyrazine formate | 东营曜康医药科技有限公司 | 2020-04-10 | — | — | CN | disclosed |
| WO-2002029021-A2 | BIOTECHNOLOGICAL METHOD FOR PREPARING CARBOXYLIC ACIDS WITH A HYDROXY-NITROGEN HETEROCYCLE | LONZA AG (CH) | 2002-04-11 | — | — | WO | disclosed |
| EP-0559116-B1 | Microbiological process for the hydroxylation of nitrogen containing heterocyclic carbonic acids | LONZA AG (CH) | 1997-05-28 | — | — | EP | disclosed |
| US-5364940-A | For treatment of sewage sludge with cultures | LONZA LTD. (CH) | 1994-11-15 | — | — | US | disclosed |
| US-5306630-A | Microbiological process for hydroxylation of nitrogen-heterocyclic-carboxylic acids | LONZA LTD. (CH) | 1994-04-26 | — | — | US | disclosed |
| US-5250548-A | Treating hypertension, heart failure | ABBOTT LABORATORIES (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0559116-A2 | Microbiological process for the hydroxylation of nitrogen containing heterocyclic carbonic acids | LONZA AG (CH) | 1993-09-08 | — | — | EP | disclosed |
| EP-0475206-A2 | Angiotensin II receptor antagonists | ABBOTT LABORATORIES (US) | 1992-03-18 | — | — | EP | disclosed |