Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16273717 | 0.89 | MRGPRX4 (0.61) | MRGPRX4HTTTP53FOLH1TSHR | |
| SCHEMBL7537186 | 0.87 | PTGDR2 (0.50) | MRGPRX4HTTTP53TSHRMEN1 | |
| SCHEMBL31568524 | 0.86 | MRGPRX4 (0.76) | MRGPRX4HTTTP53FOLH1ALDH1A1 | |
| SCHEMBL17616605 | 0.86 | MRGPRX4 (0.76) | MRGPRX4HTTTP53FOLH1ALDH1A1 | |
| SCHEMBL28816972 | 0.86 | HTT (0.53) | MRGPRX4HTTTSHRMEN1KMT2A | |
| SCHEMBL15012255 | 0.85 | PTGDR2 (0.49) | MRGPRX4HTTTP53TSHRMEN1 | |
| SCHEMBL28832475 | 0.85 | ALDH1A1 (0.46) | MRGPRX4HTTTSHRMEN1KMT2A | |
| SCHEMBL17616626 | 0.85 | TP53 (0.60) | MRGPRX4HTTTP53FOLH1PTGDR2 | |
| SCHEMBL5291219 | 0.85 | HTT (0.68) | MRGPRX4HTTTP53FOLH1PTGDR2 | |
| SCHEMBL28001736 | 0.85 | ALDH1A1 (0.50) | MRGPRX4HTTTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1094487-C | Oxime derivative and fungicide containing the same as active ingredient | SHIONOGI & CO (JP) | 2002-11-20 | — | — | CN | disclosed |
| US-6362212-B1 | POTENT FUNGICIDAL ACTIVITY | SHIONOGI & COMPANY, LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| US-20020032227-A1 | Oxime derivative and bactericide containing the same as active ingredient | TAKASE AKIRA (JP) | 2002-03-14 | — | — | US | disclosed |
| US-6268312-B1 | FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| US-6048885-A | FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0547825-B1 | Process for producing alpha-ketoamide derivative | SHIONOGI & CO (JP) | 1997-09-03 | — | — | EP | disclosed |
| EP-0754684-A1 | OXIME DERIVATIVE AND BACTERICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SHIONOGI & CO., LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5414122-A | Process for producing alpha-ketoamide derivative | SHIONOGI & CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| US-5258551-A | Amidation of benzoyl halide derivative with organic isocyanide; fungicide intermediates | SHIONOGI & CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| EP-0547825-A2 | Process for producing alpha-ketoamide derivative | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032227-A1 | Oxime derivative and bactericide containing the same as active ingredient | MSMO1, O60361, CBR1 | MRGPRX4 3876/4885HTT 3373/4885TP53 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.