Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540756 | 1.00 | SLC18A3 (0.54) | SLC18A3ALDH1A1HTR1AMAPTLMNA | |
| SCHEMBL7540353 | 0.81 | MAPT (0.52) | SLC18A3ALDH1A1HTR1AMAPTGAA | |
| SCHEMBL7540356 | 0.81 | MAPT (0.52) | SLC18A3ALDH1A1HTR1AMAPTGAA | |
| SCHEMBL11604926 | 0.81 | SLC18A3 (0.64) | SLC18A3 | |
| SCHEMBL11604923 | 0.81 | SLC18A3 (0.64) | SLC18A3 | |
| SCHEMBL11606890 | 0.81 | SLC18A3 (0.64) | SLC18A3 | |
| SCHEMBL7538963 | 0.80 | SLC18A3 (0.55) | SLC18A3ALDH1A1HTR1AMAPTLMNA | |
| SCHEMBL7538957 | 0.80 | SLC18A3 (0.55) | SLC18A3ALDH1A1HTR1AMAPTLMNA | |
| SCHEMBL7537679 | 0.80 | SLC18A3 (0.55) | SLC18A3ALDH1A1HTR1AMAPTLMNA | |
| SCHEMBL7537678 | 0.80 | SLC18A3 (0.55) | SLC18A3ALDH1A1HTR1AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1205473-A1 | VESAMICOL PIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |