SCHEMBL7540796

SCHEMBL7540796

CC(C)(C)OC(=O)N[C@@H]1CCN(Cc2ccc3ccnc(Cl)c3c2)C1=O

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
F10 P00742 17/20 0.45
F2 P00734 6/20 0.45
PRSS1 P07477 1/20 0.39
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PLG P00747 2/20 0.38
PLAT P00750 2/20 0.38
PROC P04070 2/20 0.38
SRC P12931 1/20 0.38
ROCK2 O75116 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7213552 1.00 F10 (0.45) F10F2PRSS1KMT2AL3MBTL1
SCHEMBL6435620 0.89 F10 (0.57) F10F2PRSS1
SCHEMBL7219998 0.84 F10 (0.37) F10F2PRSS1KMT2AL3MBTL1
SCHEMBL7543687 0.84 SRC (0.38) F10F2PRSS1KMT2AL3MBTL1
SCHEMBL7215755 0.83 F10 (0.49) F10F2PRSS1KMT2AL3MBTL1
SCHEMBL7213599 0.83 F10 (0.49) F10F2PLGPLATPROC
SCHEMBL7214536 0.83 F10 (0.49) F10F2PRSS1KMT2AL3MBTL1
SCHEMBL29593920 0.82 ALDH1A1 (0.51) F10F2PRSS1KMT2AL3MBTL1
SCHEMBL22911243 0.82 ALDH1A1 (0.51) F10F2PRSS1KMT2AL3MBTL1
SCHEMBL4760780 0.81 KMT2A (0.43) F10F2PRSS1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020013310-A1 Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds AVENTIS PHARMACEUTICALS PRODUCTS INC. 2002-01-31 US disclosed
US-6281227-B1 INHIBITORS OF THE ACTIVITY OF FACTOR XA. AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020013310-A1 Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds STS, ARSA, F12 F10 20/4885F2 11/4885PRSS1 67/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.