Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 2/20 | 0.30 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603721 | 0.96 | ESR1 (0.37) | ESR1ESR2MAPTNPC1RAB9A | |
| SCHEMBL7108400 | 0.81 | ESR1 (0.44) | ESR1ESR2MAPTNPC1RAB9A | |
| SCHEMBL7110268 | 0.80 | ESR1 (0.45) | ESR1ESR2MAPTNPC1RAB9A | |
| SCHEMBL7111391 | 0.77 | ALDH1A1 (0.41) | ESR1ESR2MAPTNPC1RAB9A | |
| SCHEMBL7113206 | 0.76 | ESR1 (0.48) | ESR1ESR2MAPTNPC1RAB9A | |
| SCHEMBL7107858 | 0.73 | MAPT (0.41) | ESR1ESR2MAPTNPC1RAB9A | |
| SCHEMBL7105874 | 0.71 | ESR1 (0.44) | ESR1ESR2MAPTNPC1RAB9A | |
| SCHEMBL7111006 | 0.71 | MAPT (0.51) | ESR1ESR2MAPTNPC1RAB9A | |
| SCHEMBL7107864 | 0.69 | ALDH1A1 (0.40) | ESR1ESR2MAPTNPC1RAB9A | |
| SCHEMBL7112744 | 0.68 | ESR1 (0.43) | ESR1ESR2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826670-B1 | Naphthalene compounds, intermediates, formulations, and methods | LILLY CO ELI (US) | 2002-05-08 | — | — | EP | disclosed |