SCHEMBL7540828

SCHEMBL7540828

Clc1cccc(C(Cl)c2ccccc2)c1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.56
TDO2 P48775 3/20 0.56
CYP3A4 P08684 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
NFKB1 P19838 1/20 0.48
PNMT P11086 1/20 0.48
LMNA P02545 3/20 0.47
ALDH1A1 P00352 1/20 0.47
GLA P06280 1/20 0.47
IDO2 Q6ZQW0 2/20 0.44
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ACP3 P15309 1/20 0.42
TSHR P16473 6/20 0.41
CACNA2D1 P54289 4/20 0.40
CACNA1B Q00975 4/20 0.40
CACNB1 Q02641 4/20 0.40
CACNA1G O43497 1/20 0.40
HIF1A Q16665 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29901560 0.85 IDO1 (0.53) IDO1TDO2CYP3A4LMNAALDH1A1
SCHEMBL521541 0.85 IDO1 (0.53) IDO1TDO2CYP3A4LMNAALDH1A1
SCHEMBL10798586 0.80 ACP3 (0.40) IDO1TDO2CYP3A4CYP1A2CYP2D6
SCHEMBL11828154 0.78 TSHR (0.55) IDO1TDO2CYP3A4CYP1A2CYP2D6
SCHEMBL28905220 0.78 IDO1 (0.54) IDO1TDO2CYP3A4CYP1A2CYP2D6
SCHEMBL477355 0.78 IDO1 (0.54) IDO1TDO2CYP3A4CYP1A2CYP2D6
SCHEMBL1872442 0.75 CYP1A2 (0.58) IDO1TDO2CYP3A4CYP1A2CYP2D6
SCHEMBL29500210 0.75 TSHR (0.61) IDO1TDO2CYP3A4CYP1A2CYP2D6
SCHEMBL2473425 0.75 IDO1 (0.56) IDO1TDO2CYP3A4CYP1A2CYP2D6
SCHEMBL11639869 0.73 TSHR (0.47) IDO1TDO2CYP3A4CYP1A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115403461-B Method for synthesizing benzoic acid by oxidizing ethylbenzene 吕梁学院 2023-09-22 CN disclosed
CN-115403461-A Method for synthesizing benzoic acid by oxidizing ethylbenzene 吕梁学院 2022-11-29 CN disclosed
CN-109970544-B Device and method for preparing benzoic acid from toluene 中北大学 2021-07-02 CN disclosed
CN-110026145-B Hypergravity reaction device and application thereof 中北大学 2021-05-18 CN disclosed
EP-1209147-A1 CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT TORAY INDUSTRIES, INC. (JP) 2002-05-29 EP disclosed