Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.53 |
| ▸ | TDO2 | P48775 | 3/20 | 0.53 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29901560 | 1.00 | IDO1 (0.53) | IDO1TDO2IDO2ACP3TSHR | |
| SCHEMBL11828154 | 0.93 | TSHR (0.55) | IDO1TDO2IDO2ACP3TSHR | |
| SCHEMBL11639869 | 0.87 | TSHR (0.47) | IDO1TDO2IDO2ACP3TSHR | |
| SCHEMBL7873189 | 0.86 | TSHR (0.66) | IDO1TDO2IDO2ACP3TSHR | |
| SCHEMBL11617245 | 0.85 | TSHR (0.50) | IDO1TDO2IDO2ACP3TSHR | |
| SCHEMBL7540828 | 0.85 | IDO1 (0.56) | IDO1TDO2IDO2ACP3TSHR | |
| SCHEMBL28546831 | 0.83 | TSHR (0.47) | IDO1TDO2IDO2ACP3TSHR | |
| SCHEMBL11644649 | 0.82 | TSHR (0.43) | IDO1TDO2IDO2ACP3TSHR | |
| SCHEMBL365482 | 0.81 | TSHR (0.44) | ACP3TSHRHIF1ALMNACYP2C19 | |
| SCHEMBL10799696 | 0.79 | ACP3 (0.48) | ACP3TSHRLMNACYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12492225-B2 | Melanocyte-regulating peptides | IDP DISCOVERY PHARMA, S.L. (ES) | 2025-12-09 | — | — | US | disclosed |
| US-12258423-B2 | Stapled and stitched polypeptides and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-03-25 | — | — | US | disclosed |
| CN-110105434-B | Stapled and stitched polypeptides and uses thereof | 哈佛大学的校长及成员们 | 2024-09-17 | — | — | CN | disclosed |
| US-20240294573-A1 | CONSTRAINED PEPTIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-09-05 | — | — | US | disclosed |
| CN-113861131-B | Preparation method of cetirizine impurity C | 深圳菲斯生物科技有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-113861131-B | Preparation method of cetirizine impurity C | 深圳菲斯生物科技有限公司 | 2024-04-19 | — | — | CN | disclosed |
| US-20240083943-A1 | VEGF-REGULATING PEPTIDES | IDP DISCOVERY PHARMA, S.L. (ES) | 2024-03-14 | — | — | US | disclosed |
| WO-2023227771-A1 | CYCLIC PEPTIDES WITH ANTIBACTERIAL ACTIVITY AGAINST MULTIDRUG RESISTANT (MDR) PATHOGENS | Fundación Privada Instituto De Salud Global Barcelona (ES) | 2023-11-30 | — | — | WO | disclosed |
| EP-4271480-A1 | VEGF-REGULATING PEPTIDES | IDP Discovery Pharma, S.L. (ES) | 2023-11-08 | — | — | EP | disclosed |
| CN-116964074-A | Peptides that modulate VEGF | IDP研发制药有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20100184645-A1 | STITCHED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2010-07-22 | — | — | US | disclosed |
| CN-101730708-A | stitched polypeptides | HARVARD COLLEGE | 2010-06-09 | — | — | CN | disclosed |
| WO-2010011313-A2 | LIGATION OF STAPLED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-01-28 | — | — | WO | disclosed |
| EP-2142562-A2 | STITCHED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008127480-A2 | PACKED BED MICROREACTORS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008121767-A2 | STITCHED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008028057-A2 | SHIKIMIC ACID-DERIVED COMPOUNDS FOR INHIBITION AND DETECTION OF AURORA A-ASSOCIATED TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-03-06 | — | — | WO | disclosed |
| US-5792775-A | HIGH AFFINITY FOR DOPAMINE TRANSPORTER; INHIBIT DOPAMINE UPTAKE; DO NOT HAVE A COCAINE-LIKE BEHAVORIAL PROFILE; USED TO IMAGE BINDING SITES; DIAGNOSIS AND MONITORING OF NEURODEGENERATIVE DISEASES, E.G PARKINSON'S | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-08-11 | — | — | US | disclosed |
| US-5015710-A | Catalytic addition polymerization | HERCULES INCORPORATED (US) | 1991-05-14 | — | — | US | disclosed |
| EP-0423521-A1 | Process for producing polymer molded article | HERCULES INCORPORATED (US) | 1991-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12492225-B2 | Melanocyte-regulating peptides | MC1R, MITF, MCHR1 | IDO1 102/4885TDO2 2329/4885IDO2 175/4885 |
| US-20100184645-A1 | STITCHED POLYPEPTIDES | VIP, IAPP, NGLY1 | IDO1 3069/4885TDO2 4643/4885IDO2 2961/4885 |
| US-20240294573-A1 | CONSTRAINED PEPTIDES | IAPP, NGLY1, VIP | IDO1 4036/4885TDO2 4754/4885IDO2 3867/4885 |
| US-20240083943-A1 | VEGF-REGULATING PEPTIDES | VEGFA, FLT4, FLT1 | IDO1 1488/4885TDO2 4773/4885IDO2 2343/4885 |
| US-12258423-B2 | Stapled and stitched polypeptides and uses thereof | VIP, NGLY1, IAPP | IDO1 2792/4885TDO2 3916/4885IDO2 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.