SCHEMBL754085

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16921566	0.85	NPSR1 (0.47)	NPSR1NPC1LMNARAB9AKDM4E
	SCHEMBL21333020	0.84	CES1 (0.50)	CES1NPC1RAB9AKDM4EMEN1
	SCHEMBL27861595	0.84	NPSR1 (0.46)	NPSR1NPC1LMNARAB9AKDM4E
	SCHEMBL27861674	0.81	NPSR1 (0.41)	NPSR1P4HTMNPC1LMNARAB9A
	SCHEMBL759556	0.79	ALDH1A1 (0.48)	NPSR1NPC1LMNARAB9AKDM4E
	SCHEMBL16702745	0.78	HDAC1 (0.46)	P4HTMCES1NPC1LMNARAB9A
	SCHEMBL4673459	0.78	NPSR1 (0.37)	NPSR1NPC1LMNARAB9AKDM4E
	SCHEMBL10291124	0.77	NPSR1 (0.46)	NPSR1NPC1LMNARAB9AKDM4E
	SCHEMBL757223	0.76	NPSR1 (0.43)	NPSR1P4HTMNPC1LMNARAB9A
	SCHEMBL16921568	0.76	NPSR1 (0.43)	NPSR1P4HTMNPC1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.