Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 13/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 2/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548629 | 0.86 | ITGB1 (0.55) | ITGB1ITGA5ITGA4HPGDITGB7 | |
| SCHEMBL7588676 | 0.83 | ITGB1 (0.41) | ITGB1ITGA5ITGA4POLBHPGD | |
| SCHEMBL7539479 | 0.82 | ITGB1 (0.54) | ITGB1ITGA5ITGA4ITGB2ICAM1 | |
| SCHEMBL7540918 | 0.81 | FOLH1 (0.51) | ITGB1ITGA5ITGA4ITGB7FOLH1 | |
| SCHEMBL7545114 | 0.79 | ITGB2 (0.57) | ITGB1ITGA5ITGA4ITGB7ITGAV | |
| SCHEMBL5786217 | 0.79 | ITGB1 (0.56) | ITGB1ITGA5ITGA4ITGB7ITGAV | |
| SCHEMBL7538483 | 0.78 | ITGB1 (0.50) | ITGB1ITGA5ITGA4ITGB7ITGB2 | |
| SCHEMBL7544739 | 0.78 | ITGB2 (0.56) | ITGB1ITGA5ITGA4ITGB7ITGAV | |
| SCHEMBL5787653 | 0.77 | ITGB1 (0.57) | ITGB1ITGA5ITGA4HPGDITGB7 | |
| SCHEMBL7542115 | 0.77 | TAAR1 (0.50) | ITGB1ITGA5ITGA4ITGB7ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |