Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 15/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.47 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548629 | 0.87 | ITGB1 (0.55) | FOLH1ITGB1ITGA5ITGA4ITGB7 | |
| SCHEMBL7539479 | 0.83 | ITGB1 (0.54) | FOLH1ITGB1ITGA5ITGA4 | |
| SCHEMBL7540907 | 0.81 | ITGB1 (0.46) | FOLH1ITGB1ITGA5ITGA4ITGB7 | |
| SCHEMBL7545114 | 0.80 | ITGB2 (0.57) | FOLH1ITGB1ITGA5ITGA4ITGB7 | |
| SCHEMBL7538483 | 0.79 | ITGB1 (0.50) | FOLH1ITGB1ITGA5ITGA4ITGB7 | |
| SCHEMBL7544739 | 0.79 | ITGB2 (0.56) | FOLH1ITGB1ITGA5ITGA4ITGB7 | |
| SCHEMBL7542115 | 0.78 | TAAR1 (0.50) | FOLH1ITGB1ITGA5ITGA4ITGB7 | |
| SCHEMBL8975695 | 0.76 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL10801725 | 0.76 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL7545928 | 0.76 | ITGB1 (0.53) | ITGB1ITGA5ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |