Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687107 | 0.87 | SIRT6 (0.39) | SIRT6NAPRTMAPTL3MBTL1MEN1 | |
| SCHEMBL9310457 | 0.85 | SIRT6 (0.45) | SIRT6NAPRTJUNNFKB1NFKB2 | |
| SCHEMBL27696455 | 0.82 | SIRT6 (0.42) | SIRT6NAPRTJUNNFKB1NFKB2 | |
| SCHEMBL29177447 | 0.82 | SIRT6 (0.52) | SIRT6NAPRTJUNNFKB1NFKB2 | |
| SCHEMBL29017947 | 0.79 | SIRT6 (0.40) | SIRT6NAPRTJUNNFKB1NFKB2 | |
| SCHEMBL9017636 | 0.78 | SIRT6 (0.34) | SIRT6MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL29760620 | 0.76 | KMT2A (0.49) | SIRT6NAPRTMAPTMEN1KMT2A | |
| SCHEMBL22588560 | 0.76 | KMT2A (0.49) | SIRT6NAPRTMAPTMEN1KMT2A | |
| SCHEMBL16827291 | 0.75 | SIRT6 (0.32) | SIRT6MAPTL3MBTL1 | |
| SCHEMBL4202441 | 0.75 | KMT2A (0.41) | SIRT6MAPTRAB9AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002029021-A2 | BIOTECHNOLOGICAL METHOD FOR PREPARING CARBOXYLIC ACIDS WITH A HYDROXY-NITROGEN HETEROCYCLE | LONZA AG (CH) | 2002-04-11 | — | — | WO | disclosed |