SCHEMBL7541248

SCHEMBL7541248

CC(=O)Nc1ccc(OCc2nc3cc(F)c(F)cc3s2)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.55
KMT2A Q03164 5/20 0.55
ALDH1A1 P00352 4/20 0.55
MEN1 O00255 4/20 0.55
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
ALOX5 P09917 8/20 0.55
EPHX2 P34913 8/20 0.55
L3MBTL1 Q9Y468 1/20 0.50
KDM4E B2RXH2 5/20 0.49
TDP1 Q9NUW8 4/20 0.49
RECQL P46063 2/20 0.47
GAA P10253 2/20 0.47
LMNA P02545 2/20 0.47
POLB P06746 1/20 0.47
HPGD P15428 1/20 0.47
CYP1A2 P05177 1/20 0.46
RXFP1 Q9HBX9 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7545312 0.92 MAPT (0.53) MAPTKMT2AALDH1A1MEN1NPC1
SCHEMBL7545045 0.92 MAPT (0.53) MAPTKMT2AALDH1A1MEN1NPC1
SCHEMBL7543769 0.91 ALOX5 (0.55) MAPTKMT2AALDH1A1MEN1NPC1
SCHEMBL7548790 0.88 ALOX5 (0.59) MAPTKMT2AALDH1A1MEN1NPC1
SCHEMBL7546710 0.88 MAPT (0.57) MAPTKMT2AALDH1A1MEN1NPC1
SCHEMBL7541784 0.85 ALOX5 (0.58) MAPTKMT2AALDH1A1MEN1NPC1
SCHEMBL7548568 0.84 NPC1 (0.61) MAPTKMT2AALDH1A1MEN1NPC1
SCHEMBL7543452 0.84 NPC1 (0.58) MAPTKMT2AALDH1A1MEN1NPC1
SCHEMBL7542768 0.84 MAPT (0.64) MAPTKMT2AALDH1A1MEN1NPC1
SCHEMBL7550272 0.84 ALOX5 (0.53) MAPTKMT2AALDH1A1MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0795550-B1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO CO (JP) 2002-06-05 EP disclosed
US-5736487-A HERBICIDES SANKYO COMPANY, LIMITED (JP) 1998-04-07 US disclosed
EP-0795550-A1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed