Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28832537 | 0.81 | AKR1B1 (0.32) | AKR1B1 | |
| SCHEMBL28832538 | 0.81 | AKR1B1 (0.32) | AKR1B1 | |
| SCHEMBL28658954 | 0.72 | AKR1B1 (0.39) | AKR1B1 | |
| SCHEMBL5576855 | 0.72 | AKR1B1 (0.39) | AKR1B1 | |
| SCHEMBL27719820 | 0.72 | — | — | |
| SCHEMBL184297 | 0.72 | AKR1B1 (0.42) | AKR1B1 | |
| SCHEMBL27688172 | 0.72 | AKR1B1 (0.42) | AKR1B1 | |
| SCHEMBL5382389 | 0.70 | AKR1B1 (0.40) | AKR1B1 | |
| SCHEMBL22692164 | 0.70 | AKR1B1 (0.40) | AKR1B1 | |
| SCHEMBL14323419 | 0.70 | AKR1B1 (0.40) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732338-B1 | 2,2-Difluoro-3-carbamoyl ribose sulfonate compounds and process for the preparation of beta nucleosides | LILLY CO ELI (US) | 2002-05-15 | — | — | EP | disclosed |
| EP-0732338-A1 | 2,2-Difluoro-3-carbamoyl ribose sulfonate compounds and process for the preparation of beta nucleosides | ELI LILLY AND COMPANY (US) | 1996-09-18 | — | — | EP | disclosed |
| US-5521294-A | 2,2-difluoro-3-carbamoyl ribose sulfonate compounds and process for the preparation of beta nucleosides | ELI LILLY AND COMPANY (US) | 1996-05-28 | — | — | US | disclosed |