SCHEMBL754151

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4355540	0.86	UHRF1 (0.54)	NR3C2UHRF1FFAR1DYRK1AKCNQ2
	SCHEMBL25918287	0.85	UHRF1 (0.42)	NR3C2PTGS1PTGS2UHRF1WNT3A
	SCHEMBL1563414	0.81	NR3C2 (0.49)	NR3C2UHRF1FFAR1KCNQ2
	Bromide SCHEMBL11513156	0.79	NR3C2 (0.47)	NR3C2UHRF1FFAR1KCNQ2
	Bromide SCHEMBL10618379	0.79	NR3C2 (0.47)	NR3C2UHRF1FFAR1KCNQ2
	SCHEMBL4358691	0.78	UHRF1 (0.50)	NR3C2UHRF1FFAR1DYRK1AKCNQ2
	SCHEMBL487318	0.76	UHRF1 (0.48)	NR3C2UHRF1FFAR1DYRK1AKCNQ2
	SCHEMBL25211830	0.76	FFAR1 (0.49)	NR3C2FFAR1
	SCHEMBL26944235	0.76	UHRF1 (0.43)	NR3C2UHRF1WNT3AFFAR1DYRK1A
	SCHEMBL13754972	0.75	PTGS1 (0.46)	NR3C2PTGS1PTGS2TAAR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.