Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044157 | 0.81 | MEN1 (0.41) | MEN1CYP3A4ALOX15KMT2APTPN2 | |
| SCHEMBL5187745 | 0.73 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2APTPN2 | |
| SCHEMBL5188905 | 0.73 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2APTPN2 | |
| SCHEMBL11668697 | 0.71 | ALOX15 (0.47) | MEN1CYP3A4ALOX15KMT2APTPN2 | |
| SCHEMBL11703729 | 0.70 | MEN1 (0.53) | MEN1CYP3A4ALOX15KMT2APTPN2 | |
| SCHEMBL125579 | 0.69 | MEN1 (0.36) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL16084847 | 0.69 | MEN1 (0.46) | MEN1CYP3A4ALOX15KMT2APTPN2 | |
| SCHEMBL2045378 | 0.69 | MEN1 (0.41) | MEN1CYP3A4ALOX15KMT2APTPN2 | |
| SCHEMBL20607595 | 0.68 | MEN1 (0.46) | MEN1CYP3A4ALOX15KMT2APTPN2 | |
| SCHEMBL20607596 | 0.68 | MEN1 (0.46) | MEN1CYP3A4ALOX15KMT2APTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1129567-C | Process for preparation of cyclopropylacetylene derivatives | KURARAY CO (JP) | 2003-12-03 | — | — | CN | disclosed |
| EP-0936207-B1 | Process for the preparation of cyclopropylacetylene derivatives | KURARAY CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-6180835-B1 | RETRO-ETHYNYLATION PROCESS OF A CYCLOPROPYLPROPYNOL COMPOUND; PREPARING AN INTERMEDIATE IN SYNTHESIS OF DRUG HAVING ANTI-HIV ACTIVITY | KURARAY CO., LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| CN-1232815-A | Process for preparation of cyclopropylacetylene derivatives | KURARAY CO (JP) | 1999-10-27 | — | — | CN | disclosed |
| EP-0936207-A2 | Process for the preparation of cyclopropylacetylene derivatives | KURARAY CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |