SCHEMBL7541558

SCHEMBL7541558

CCCCCOc1cccc(C=Cc2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 1/20 0.61
TLR2 O60603 1/20 0.61
LTA4H P09960 2/20 0.56
TSHR P16473 1/20 0.55
LCK P06239 1/20 0.55
AHR P35869 1/20 0.53
CHRNA7 P36544 3/20 0.51
CHRNA10 Q9GZZ6 3/20 0.51
CHRNA9 Q9UGM1 3/20 0.51
CYSLTR2 Q9NS75 1/20 0.51
SMPD1 P17405 3/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7539459 0.98 TLR4 (0.59) TLR4TLR2LTA4HTSHRLCK
SCHEMBL7541623 0.90 LCK (0.58) TLR4TLR2LCKCHRNA7CHRNA10
SCHEMBL7541618 0.90 LCK (0.58) TLR4TLR2LCKCHRNA7CHRNA10
SCHEMBL17864841 0.84 TLR4 (0.65) TLR4TLR2LTA4HTSHRLCK
SCHEMBL677283 0.83 TSHR (0.58) TLR4TLR2LTA4HTSHRCYSLTR2
SCHEMBL5740101 0.83 CHRNA7 (0.68) LTA4HAHRCHRNA7CHRNA10CHRNA9
SCHEMBL7538209 0.83 CHRNA7 (0.68) LTA4HAHRCHRNA7CHRNA10CHRNA9
SCHEMBL5739190 0.83 CHRNA7 (0.68) LTA4HAHRCHRNA7CHRNA10CHRNA9
SCHEMBL5740096 0.83 CHRNA7 (0.68) LTA4HAHRCHRNA7CHRNA10CHRNA9
SCHEMBL5739187 0.83 CHRNA7 (0.68) LTA4HAHRCHRNA7CHRNA10CHRNA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020015906-A1 Polymer for photoresist, method of production thereof and photoresist composition containing polymer SAMSUNG ELECTRONICS CO., LTD. (KR) 2002-02-07 US disclosed