Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.76 |
| ▸ | RAB9A | P51151 | 5/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | EPHX2 | P34913 | 12/20 | 0.75 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544458 | 0.88 | NPC1 (0.79) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7544973 | 0.87 | NPC1 (0.77) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8769691 | 0.87 | EPHX2 (0.84) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7542600 | 0.86 | NPC1 (1.00) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7543728 | 0.86 | EPHX2 (0.78) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7541206 | 0.85 | NPC1 (0.74) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7551599 | 0.84 | NPC1 (0.76) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7541535 | 0.84 | ALDH1A1 (0.80) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7540872 | 0.84 | NPC1 (0.79) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7545168 | 0.83 | NPC1 (0.71) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |