Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544351 | 0.92 | DYRK1A (0.52) | DYRK1APDPK1EPHX2ALOX5NPC1 | |
| SCHEMBL7544292 | 0.90 | DYRK1A (0.52) | DYRK1APTPN1EPHX2ALOX5MAPT | |
| SCHEMBL7549484 | 0.89 | EPHX2 (0.43) | DYRK1APDPK1EPHX2ALOX5MAPT | |
| SCHEMBL7541627 | 0.87 | NPC1 (0.55) | DYRK1AEPHX2ALOX5MAPTSMN1; SMN2 | |
| SCHEMBL7550313 | 0.85 | NPC1 (0.58) | EPHX2ALOX5MAPTSMN1; SMN2NPC1 | |
| SCHEMBL7545175 | 0.84 | ALOX5 (0.60) | DYRK1APDPK1PTPN1EPHX2ALOX5 | |
| SCHEMBL7550271 | 0.83 | DYRK1A (0.52) | DYRK1AEPHX2ALOX5MAPTNPC1 | |
| SCHEMBL7541521 | 0.82 | SMN1; SMN2 (0.50) | DYRK1APDPK1EPHX2ALOX5MAPT | |
| SCHEMBL7550288 | 0.82 | EPHX2 (0.52) | DYRK1AEPHX2ALOX5SMN1; SMN2KDM4E | |
| SCHEMBL7541020 | 0.81 | DYRK1A (0.54) | DYRK1AEPHX2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |