Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30539936 | 0.84 | KDM4E (0.46) | TLR7HTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL15924790 | 0.78 | TLR7 (0.47) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9602914 | 0.78 | TLR7 (0.47) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15924453 | 0.78 | TLR7 (0.47) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10587719 | 0.78 | TLR7 (0.47) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11709817 | 0.77 | HTR2A (0.54) | TLR8HTR2AHTR2CCDK4CCND1 | |
| SCHEMBL9412483 | 0.76 | KDM4E (0.50) | TLR7HTR2CHTR2BKDM4EGPR3 | |
| SCHEMBL28004657 | 0.75 | KDM4E (0.37) | TLR7HTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL2029970 | 0.74 | PDE4A (0.47) | TLR7PDE4APDE4BPDE4CPDE4D | |
| Quinoline SCHEMBL27614414 | 0.74 | HTR2A (0.48) | TLR8MPOHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966466-B1 | PYRROLO 3,2-c]QUINOLINE DERIVATIVES CONTAINING HALOALKOXY GROUP AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | KOREA RES INST CHEM TECH (KR) | 2002-07-03 | — | — | EP | disclosed |
| US-6011044-A | ANTIULCER AGENTS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2000-01-04 | — | — | US | disclosed |
| EP-0966466-A1 | PYRROLO 3,2-c]QUINOLINE DERIVATIVES CONTAINING HALOALKOXY GROUP AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-12-29 | — | — | EP | disclosed |
| WO-1999009029-A1 | PYRROLO[3,2-c]QUINOLINE DERIVATIVES CONTAINING HALOALKOXY GROUP AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-02-25 | — | — | WO | disclosed |