Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | HTR2B | P41595 | 5/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882915 | 0.75 | KDM4E (0.43) | KDM4EGPR3ERN1ADORA3KMT2A | |
| SCHEMBL30539936 | 0.75 | KDM4E (0.46) | KDM4EGPR3HTR2AHTR2CHTR2B | |
| SCHEMBL7541745 | 0.75 | TLR7 (0.47) | KDM4EGPR3HTR2AHTR2CHTR2B | |
| SCHEMBL27565238 | 0.70 | CDK4 (0.61) | HTR2AHTR2CRAB9ASMN1; SMN2LMNA | |
| SCHEMBL9412483 | 0.70 | KDM4E (0.50) | KDM4EGPR3HTR2CHTR2BADORA3 | |
| SCHEMBL31248574 | 0.69 | MAOB (0.46) | SMN1; SMN2LMNATLR7CYP2C9HTT | |
| SCHEMBL16415979 | 0.67 | KDM4E (0.50) | KDM4EGPR3ERN1ADORA3LMNA | |
| SCHEMBL28127373 | 0.66 | P2RX7 (0.42) | — | |
| SCHEMBL5635938 | 0.65 | KDM4E (0.44) | KDM4EGPR3ERN1ADORA3KMT2A | |
| SCHEMBL27524213 | 0.65 | ERN1 (0.44) | KDM4EGPR3ERN1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104321330-A | Rhodium catalyst and process for producing amine compound | TAKEDA PHARMACEUTICAL | 2015-01-28 | — | — | CN | disclosed |