Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 10/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538486 | 1.00 | TDP1 (0.48) | TDP1ATMNPSR1KMT2AMAPT | |
| SCHEMBL7544858 | 0.97 | TDP1 (0.52) | TDP1ATMNPSR1KMT2AMAPT | |
| SCHEMBL7545229 | 0.97 | TDP1 (0.52) | TDP1ATMNPSR1KMT2AMAPT | |
| SCHEMBL7541875 | 0.87 | TAS1R3 (0.47) | ALDH1A1 | |
| SCHEMBL21376478 | 0.86 | SYK (0.43) | ATMPOLBALDH1A1GAADRD2 | |
| SCHEMBL7544009 | 0.83 | TAS1R3 (0.52) | — | |
| SCHEMBL20024957 | 0.83 | ITGB1 (0.59) | — | |
| SCHEMBL7539797 | 0.82 | TAS1R3 (0.51) | — | |
| SCHEMBL7547233 | 0.82 | TAS1R3 (0.43) | — | |
| SCHEMBL7542016 | 0.81 | TAS1R3 (0.50) | KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |