SCHEMBL7541984

SCHEMBL7541984

CC(C)CCC(OC(=O)c1ccc(O)cc1F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.43
CA1 P00915 6/20 0.43
CA2 P00918 6/20 0.43
CA7 P43166 6/20 0.43
CA9 Q16790 6/20 0.43
CA14 Q9ULX7 6/20 0.43
ESRRG P62508 1/20 0.36
PDK2 Q15119 1/20 0.34
PDK4 Q16654 1/20 0.34
ALDH1A1 P00352 3/20 0.34
SERPINE1 P05121 1/20 0.33
SCN8A Q9UQD0 1/20 0.32
SCN10A Q9Y5Y9 1/20 0.32
LMNA P02545 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
ABHD6 Q9BV23 1/20 0.32
MAPK1 P28482 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7541987 1.00 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL9745293 0.84 ALDH1A1 (0.40) CA12CA1CA2CA7CA9
SCHEMBL9125115 0.84 ALDH1A1 (0.40) CA12CA1CA2CA7CA9
SCHEMBL7609522 0.84 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL7609521 0.84 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL7541015 0.83 PRSS1 (0.39) ALDH1A1MAPK1KDM4EKMT2A
SCHEMBL7541010 0.83 PRSS1 (0.39) ALDH1A1MAPK1KDM4EKMT2A
SCHEMBL8107463 0.82 CA12 (0.36) CA12CA1CA2CA7CA9
SCHEMBL8821926 0.82 CA12 (0.36) CA12CA1CA2CA7CA9
SCHEMBL8107467 0.82 CA12 (0.36) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0937765-B1 Ferrielectric liquid crystal compound MITSUBISHI GAS CHEMICAL CO (JP) 2002-05-29 EP disclosed
EP-0853076-B1 Liquid crystal compound MITSUBISHI GAS CHEMICAL CO (JP) 2001-09-12 EP disclosed
US-6128065-A 2 OR 3-FLUORO SUBSTITUTED OR UNSUBSTITUTED 4-(1-TRIFLUOROMETHYL-4-METHYL-PENTYL OR HEXYLOXYCARBONYL)PHENYL-4'-N-ALKYLBIPHENYL-4-CARBOXYLATE CONTAINING ASYMMETRIC CARBON ATOM MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2000-10-03 US disclosed
US-6002042-A Liquid crystal compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1999-12-14 US disclosed
EP-0937765-A1 Ferrielectric liquid crystal compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1999-08-25 EP disclosed
EP-0853076-A1 Liquid crystal compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-07-15 EP disclosed