Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | DNM2 | P50570 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.37 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11789553 | 0.90 | CYP1A2 (0.61) | CYP1A2CYP2C19DNM2KMT2AMAPT | |
| SCHEMBL12645019 | 0.84 | KMT2A (0.54) | DNM2KMT2AMAPTHTTNPSR1 | |
| SCHEMBL8050374 | 0.84 | KMT2A (0.59) | DNM2KMT2AMAPTHTTNPSR1 | |
| SCHEMBL10921270 | 0.83 | CYP1A2 (0.65) | CYP1A2CYP2C19GAAKMT2AMAPT | |
| SCHEMBL1130832 | 0.79 | CYP1A2 (0.65) | CYP1A2CYP2C19GAAMAPTHTT | |
| SCHEMBL5085800 | 0.78 | CYP1A2 (0.80) | CYP1A2CYP2C19KMT2AMAPTHTT | |
| SCHEMBL21940998 | 0.78 | KCNH3 (0.60) | CYP1A2CYP2C19KMT2AMAPTNPSR1 | |
| SCHEMBL24325488 | 0.77 | TLR8 (0.50) | DNM2KMT2AKCNH3 | |
| SCHEMBL20805828 | 0.77 | KMT2A (0.69) | DNM2KMT2AKCNH3LMNA | |
| SCHEMBL17717349 | 0.77 | KMT2A (0.55) | DNM2KMT2AMAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711760-B1 | METHOD OF ALKYLATING TRIAZINE DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2002-05-15 | — | — | EP | disclosed |
| US-6130332-A | USING A GROUP 8 METAL CATALYST AND ALDEHYDES OR KETONE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-10-10 | — | — | US | disclosed |
| US-5792867-A | Method of alkylating of triazine derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0760369-A1 | PROCESS FOR ALKYLATING TRIAZINE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0711760-A1 | METHOD OF ALKYLATING TRIAZINE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |