Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 14/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542372 | 1.00 | IL6ST (0.40) | IL6STRENIDH1KLK7CTSL | |
| SCHEMBL7542377 | 1.00 | IL6ST (0.40) | IL6STRENIDH1KLK7CTSL | |
| SCHEMBL7358577 | 0.85 | IL6ST (0.38) | IL6ST | |
| SCHEMBL7364612 | 0.80 | CSNK2B (0.33) | RENKLK7 | |
| SCHEMBL7360651 | 0.80 | PPARA (0.33) | RENKLK7 | |
| SCHEMBL7364607 | 0.80 | CSNK2B (0.33) | RENKLK7 | |
| SCHEMBL7364609 | 0.80 | CSNK2B (0.33) | RENKLK7 | |
| SCHEMBL7360653 | 0.80 | PPARA (0.33) | RENKLK7 | |
| SCHEMBL7360648 | 0.80 | PPARA (0.33) | RENKLK7 | |
| SCHEMBL7358582 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |