Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 9/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 2/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | RABGGTB | P53611 | 1/20 | 0.31 |
| ▸ | RABGGTA | Q92696 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364609 | 1.00 | CSNK2B (0.33) | CSNK2BCSNK2A1RENPPARAPPARG | |
| SCHEMBL7364612 | 1.00 | CSNK2B (0.33) | CSNK2BCSNK2A1RENPPARAPPARG | |
| SCHEMBL7360651 | 0.91 | PPARA (0.33) | CSNK2BCSNK2A1RENPPARAPPARG | |
| SCHEMBL7360648 | 0.91 | PPARA (0.33) | CSNK2BCSNK2A1RENPPARAPPARG | |
| SCHEMBL7360653 | 0.91 | PPARA (0.33) | CSNK2BCSNK2A1RENPPARAPPARG | |
| SCHEMBL7365061 | 0.83 | REN (0.33) | RENPPARAPPARG | |
| SCHEMBL7365066 | 0.83 | REN (0.33) | RENPPARAPPARG | |
| SCHEMBL7365064 | 0.83 | REN (0.33) | RENPPARAPPARG | |
| SCHEMBL7542372 | 0.80 | IL6ST (0.40) | RENKLK7 | |
| SCHEMBL7542380 | 0.80 | IL6ST (0.40) | RENKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |