Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27537229 | 1.00 | KDM4E (0.47) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL27520737 | 0.85 | TACR1 (0.41) | THRBLMNAALDH1A1PRMT6L3MBTL1 | |
| SCHEMBL4389856 | 0.83 | TNF (0.46) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL27546548 | 0.83 | KDM4E (0.46) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL6872282 | 0.81 | KDM4E (0.44) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL27551751 | 0.80 | ALOX15 (0.42) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL7362447 | 0.75 | CYP2C19 (0.60) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL7362451 | 0.75 | CYP2C19 (0.60) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2921395 | 0.75 | PRSS1 (0.47) | KDM4EMAPTTHRBRECQLALDH1A1 | |
| SCHEMBL28318850 | 0.73 | SLC7A5 (0.47) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837877-B8 | L-ASPARTYL-L-THIENYLALANINE METHYL ESTERS, PROCESS FOR PRODUCING THEM AND THEIR USE AS SWEETENERS | PHARMACON FORSCHUNG & BERATUNG GMBH (AT) | 2002-05-15 | — | — | EP | disclosed |
| EP-0837877-B1 | L-ASPARTYL-L-THIENYLALANINE METHYL ESTERS, PROCESS FOR PRODUCING THEM AND THEIR USE AS SWEETENERS | PHARMACON FORSCHUNG & BERATUNG GMBH (AT) | 2001-08-16 | — | — | EP | disclosed |
| EP-0837877-A1 | L-ASPARTYL-L-THIENYLALANINE METHYL ESTERS, PROCESS FOR PRODUCING THEM AND THEIR USE AS SWEETENERS | HOLLAND SWEETENER COMPANY V.O.F. (NL) | 1998-04-29 | — | — | EP | disclosed |
| WO-1996037507-A1 | L-ASPARTYL-L-THIENYLALANINE METHYL ESTERS, PROCESS FOR PRODUCING THEM AND THEIR USE AS SWEETENERS | HOLLAND SWEETENER COMPANY V.O.F. (NL) | 1996-11-28 | — | — | WO | disclosed |