SCHEMBL7542473

SCHEMBL7542473

CNC(=O)/C(=N/OC)c1ccccc1/C(ON)=C(C)/C(=N\OC)c1ccc(F)cc1C

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.35
MAPK13 O15264 1/20 0.31
MAPK12 P53778 1/20 0.31
MAPK11 Q15759 1/20 0.31
MAPK14 Q16539 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
PKM P14618 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7498105 0.90 HIF1A (0.39) RAB9ANPC1KMT2APOLBMAPK13
SCHEMBL7500236 0.86 IDO1 (0.31) GAA
SCHEMBL7501814 0.85 HIF1A (0.35) RAB9ANPC1KMT2AKDM4EMAPT
SCHEMBL7498630 0.83 CPS1 (0.37) RAB9ANPC1KMT2AMAPTSMN1; SMN2
SCHEMBL6703061 0.81 HIF1A (0.39) MAPK14KDM4EMAPTPKMGAA
SCHEMBL7504767 0.80 PARP14 (0.36) KDM4ELMNA
SCHEMBL7740767 0.77 HIF1A (0.32)
SCHEMBL7542482 0.77 HIF1A (0.40) RAB9ANPC1KMT2APOLBKDM4E
SCHEMBL7492764 0.76 HIF1A (0.39) RAB9ANPC1KMT2AMAPTSMN1; SMN2
SCHEMBL5079843 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6420423-B1 PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH BAYER AKTIENGESELLSCHAFT (DE) 2002-07-16 US disclosed
EP-1207152-A2 Pesticides Bayer Aktiengesellschaft (DE) 2002-05-22 EP disclosed
US-5985921-A OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS NOVARTIS CORPORATION (US) 1999-11-16 US disclosed
EP-0865424-A1 PESTICIDES Novartis AG (CH) 1998-09-23 EP disclosed
WO-1997020809-A1 PESTICIDES NOVARTIS AG (CH) 1997-06-12 WO disclosed