Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498106 | 0.90 | HIF1A (0.51) | HIF1APTGS2MMP1RAB9ANPC1 | |
| SCHEMBL7713710 | 0.88 | HIF1A (0.42) | HIF1APTGS2RAB9ANPC1POLB | |
| SCHEMBL7713711 | 0.88 | HIF1A (0.42) | HIF1APTGS2RAB9ANPC1POLB | |
| SCHEMBL17937978 | 0.88 | HIF1A (0.42) | HIF1APTGS2RAB9ANPC1POLB | |
| SCHEMBL7500240 | 0.86 | HIF1A (0.40) | HIF1APTGS2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7501818 | 0.86 | HIF1A (0.45) | HIF1ARAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL7493427 | 0.84 | HIF1A (0.43) | HIF1A | |
| SCHEMBL7498636 | 0.84 | HIF1A (0.42) | HIF1ALMNAPKMGAA | |
| SCHEMBL13148667 | 0.83 | HIF1A (0.46) | HIF1APTGS2KMT2ALMNA | |
| SCHEMBL7171770 | 0.83 | HIF1A (0.43) | HIF1APTGS2RAB9AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420423-B1 | PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |
| EP-1207152-A2 | Pesticides | Bayer Aktiengesellschaft (DE) | 2002-05-22 | — | — | EP | disclosed |
| US-5985921-A | OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS | NOVARTIS CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |