Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541544 | 0.86 | PTGS2 (0.66) | PTGS2PTGS1MMP1MMP2MMP9 | |
| SCHEMBL7540369 | 0.85 | PTGS2 (0.49) | PTGS2PTGS1MMP1MMP2MMP3 | |
| SCHEMBL7538559 | 0.84 | PTGS2 (0.46) | PTGS2PTGS1MMP1MMP2MMP3 | |
| SCHEMBL7540175 | 0.84 | PTGS2 (0.50) | PTGS2PTGS1MMP1MMP2MMP3 | |
| SCHEMBL7543918 | 0.81 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL7048728 | 0.73 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL12520277 | 0.72 | KMT2A (0.65) | — | |
| SCHEMBL6721428 | 0.72 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL6725527 | 0.71 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL6733516 | 0.70 | PTGS2 (0.50) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993002057-A1 | RETROVIRAL PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-04 | — | — | WO | disclosed |