Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542677 | 1.00 | NR1I2 (0.51) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL7643450 | 0.91 | NR1I2 (0.41) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL7643449 | 0.91 | NR1I2 (0.41) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL6542726 | 0.89 | KCNH2 (0.43) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL7225660 | 0.89 | KCNH2 (0.43) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL7225657 | 0.89 | KCNH2 (0.43) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL6542731 | 0.89 | KCNH2 (0.43) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL8443056 | 0.89 | NR1I2 (0.41) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL8443059 | 0.89 | NR1I2 (0.41) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9363531 | 0.89 | NR1I2 (0.41) | NR1I2PPARGPGRESR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468995-B1 | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0667868-B1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-05-15 | — | — | EP | disclosed |
| US-20010056089-A1 | Novel crystal of cephalosporin compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-27 | — | — | US | disclosed |
| US-20010007903-A1 | NOVEL CRYSTAL OF CEPHALOSPORIN COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-12 | — | — | US | disclosed |
| EP-0780393-A1 | NOVEL CRYSTAL OF CEPHALOSPORIN COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0667868-A1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-23 | — | — | EP | disclosed |
| WO-1995007283-A1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056089-A1 | Novel crystal of cephalosporin compound | CEP170, CXXC4, DAO | NR1I2 1416/4885PPARG 4172/4885PGR 4818/4885 |
| US-20010007903-A1 | NOVEL CRYSTAL OF CEPHALOSPORIN COMPOUND | CEP170, CXXC4, DAO | NR1I2 1416/4885PPARG 4172/4885PGR 4818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.