SCHEMBL7542686

SCHEMBL7542686

O=C1[C@@H](NS(=O)(=O)c2cc3ccccc3s2)CCN1Cc1csc2ccnc(Cl)c12

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.55
F2 P00734 8/20 0.55
PROC P04070 7/20 0.55
PLG P00747 7/20 0.55
PLAT P00750 6/20 0.55
PRSS1 P07477 5/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7542319 0.85 F10 (0.54) F10F2PROCPLGPLAT
Trifluoroacetic Acid SCHEMBL7383804 0.85 F10 (0.54) F10F2PROCPLGPLAT
SCHEMBL7540352 0.81 F10 (0.68) F10F2PROCPLGPLAT
SCHEMBL7544799 0.78 F10 (0.62) F10F2PROCPLGPLAT
SCHEMBL7540142 0.77 F10 (0.65) F10F2PROCPLGPLAT
SCHEMBL7214244 0.76 F10 (0.65) F10F2PROCPLGPLAT
SCHEMBL7541684 0.75 F10 (0.63) F10F2PROCPLGPLAT
SCHEMBL27567980 0.73 F10 (0.73) F10F2PROCPLGPLAT
SCHEMBL7539268 0.73 F10 (0.63) F10F2PROCPLGPLAT
SCHEMBL7213494 0.73 F10 (0.38) F10F2PROCPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020013310-A1 Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds AVENTIS PHARMACEUTICALS PRODUCTS INC. 2002-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020013310-A1 Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds STS, ARSA, F12 F10 20/4885F2 11/4885PROC 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.