Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 6/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.41 |
| ▸ | ITGAL | P20701 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549315 | 0.91 | ITGB2 (0.42) | TACR1ITGB2ICAM1ITGALERAP2 | |
| SCHEMBL7540043 | 0.91 | TACR1 (0.46) | TACR1ITGB2ICAM1ITGALERAP2 | |
| SCHEMBL7541000 | 0.90 | ITGB2 (0.42) | TACR1ITGB2ICAM1ITGALERAP2 | |
| SCHEMBL7538530 | 0.90 | ITGB2 (0.48) | ITGB2ICAM1ITGALHPGDITGB1 | |
| SCHEMBL7539177 | 0.89 | ITGB2 (0.49) | TACR1ITGB2ICAM1ITGALERAP2 | |
| SCHEMBL7538745 | 0.89 | ITGB2 (0.45) | TACR1ITGB2ICAM1ITGALERAP2 | |
| SCHEMBL7545077 | 0.88 | ITGB2 (0.51) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7544261 | 0.88 | ITGB2 (0.51) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7539842 | 0.88 | ITGB2 (0.51) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL7544703 | 0.88 | ITGB2 (0.51) | ITGB2ICAM1ITGALITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |