Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 8/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 8/20 | 0.42 |
| ▸ | ITGAL | P20701 | 8/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542032 | 0.92 | FPR2 (0.41) | ITGB2ICAM1ITGALERAP2TACR1 | |
| SCHEMBL7549315 | 0.91 | ITGB2 (0.42) | ITGB2ICAM1ITGALERAP2NPC1 | |
| SCHEMBL7540043 | 0.91 | TACR1 (0.46) | ITGB2ICAM1ITGALERAP2TACR1 | |
| SCHEMBL7542690 | 0.90 | TACR1 (0.43) | ITGB2ICAM1ITGALERAP2TACR1 | |
| SCHEMBL7538530 | 0.90 | ITGB2 (0.48) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL7545879 | 0.89 | ITGB2 (0.49) | ITGB2ICAM1ITGALERAP2KMT2A | |
| SCHEMBL7538511 | 0.87 | ITGB1 (0.47) | ITGB2ICAM1ITGAL | |
| SCHEMBL7545203 | 0.87 | ITGB2 (0.43) | ITGB2ICAM1ITGALERAP2TACR1 | |
| SCHEMBL7541018 | 0.87 | KMT2A (0.45) | ITGB2ICAM1ITGALTACR1MEN1 | |
| SCHEMBL7542026 | 0.86 | ITGB2 (0.54) | ITGB2ICAM1ITGALMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |