Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.38 |
| ▸ | CTSS | P25774 | 4/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 4/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546039 | 0.94 | CTSK (0.43) | CTSKCTSSCTSLCTSBGAA | |
| SCHEMBL7542622 | 0.93 | CTSK (0.39) | CTSKCTSSFOLH1CTSLCTSB | |
| SCHEMBL7547045 | 0.93 | CTSK (0.39) | CTSKCTSSCTSLMAPK1ALDH1A1 | |
| SCHEMBL7570937 | 0.92 | CTSK (0.35) | CTSKCTSSFFAR2GRNSORT1 | |
| SCHEMBL7566389 | 0.92 | CTSK (0.35) | CTSKCTSSFOLH1FFAR2GRN | |
| SCHEMBL7538332 | 0.92 | CTSK (0.35) | CTSKCTSSFFAR2GRNSORT1 | |
| SCHEMBL7568018 | 0.92 | CTSK (0.35) | CTSKCTSSFOLH1FFAR2GRN | |
| SCHEMBL7541723 | 0.91 | CTSK (0.38) | CTSKCTSSFFAR2GRNSORT1 | |
| SCHEMBL7566382 | 0.91 | ACE (0.36) | CTSKCTSSFOLH1FFAR2GRN | |
| SCHEMBL7541309 | 0.91 | ANPEP (0.40) | CTSKCTSSCTSLLMNACTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |